LC-MS Method Development

Bioanalytical LC-MS method development for quantitative determination of drugs and their metabolites in biological fluids is crucial during drug development. LC-MS uses its sensitivity and specificity to detect and quantify compounds accurately. The need for efficiently generated, regulatory compliant bioanalytical data is reliant on fit-for-purpose methods being developed and validated by experienced LC-MS scientists. 

LC-MS uses
Our bioanalysis LC-MS method development teams are recognized for the ability to efficiently develop and validate routine and non-routine methods in a wide variety of matrices and uses, and to rapidly employ these assays in a GLP-compliant, high throughput sample analysis environment. 
As pioneers in applying this technology to quantitative analysis for Good Laboratory Practice (GLP) studies, our extensive lab background and expertise combined with a high level of commitment to customer service, have established Intertek as a premier bioanalytical LC-MS resource for the pharmaceutical industry. 

LC-MS method development lab expertise includes:

• Liquid/Liquid, SPE and Protein Precipitation in 96-Well and Standard Formats
• Hydrophilic Interaction Chromatography (HILIC)
• Ion Exchange Solid Phase Extraction (SPE) and Chromatography
• Chiral Analysis
• Analysis of Drugs in Ocular Tissues
• Biodistribution studies
• Analysis of Peptides and Pegylated Drugs and Metabolites
• High Throughput Automated Liquid handling Using Hamilton Microlab StarLET Systems

Partner with our expert LC-MS method development team for reliable, GLP-compliant bioanalysis—contact us today.